guanosine 5'-diphosphate sodium salt

Names

[ Name ]:
guanosine 5'-diphosphate sodium salt

[Synonym ]:
guanosine 5'-diphosphate sodium salt,Type I
GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT
guanosine 5'-diphosphate sodium type I
5'-GDP 3NA
GUANOSINE-5'-DIPHOSPHATE SODIUM SALT ULTRA PURE GRADE
Guanosine-5''-diphosphoric acid monosodium salt

Biological Activity

[Description]:

Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[Target]

Human Endogenous Metabolite

[References]

[1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418.

[2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₄N₅NaO₁₁P₂

[ Molecular Weight ]:
465.18200

[ Exact Mass ]:
465.00600

[ PSA ]:
275.02000

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography.

J. Chromatogr. A. 1360 , 240-7, (2014)

Glucaminium-based ionic liquids are a new class of recently developed ionic liquids and prepared by functionalizing the amine group of N-methyl-d-glucamine, which renders them good hydrophilicity due ...

ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence.

Biochim. Biophys. Acta 1837(12) , 2017-30, (2014)

Whether active UCP1 can reduce ROS production in brown-fat mitochondria is presently not settled. The issue is of principal significance, as it can be seen as a proof- or disproof-of-principle concern...

Differential kinetics at PK/PEPCK branch point in the cestode, Raillietina echinobothrida.

Exp. Parasitol. 153 , 151-9, (2015)

Pyruvate kinase (PK; EC 2.7.1.40) and phosphoenolpyruvate carboxykinase (PEPCK; EC 4.1.1.32) are essential regulatory enzymes of glucose oxidation in helminths, the PK/PEPCK branch point being the fir...

Related Compounds

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