S-(2-Carboxyethyl)-L-cysteine

Names

[ Name ]:
S-(2-Carboxyethyl)-L-cysteine

[Synonym ]:
S-(2-Carboxyethyl)-L-cysteine
(2R)-2-amino-3-(2-carboxyethylsulfanyl)propanoic acid
S-Carboxyethyl-L-cysteine
3-[(2-Carboxyethyl)thio]alanine
L-3-((2-Carboxyethyl)thio)alanine
L-Cysteine, S-(2-carboxyethyl)-

Biological Activity

[Description]:

S-(2-Carboxyethyl)-L-cysteine (S-Carboxyethylcysteine) is a non-protein (modified) sulfur amino acid. S-(2-Carboxyethyl)-L-cysteine is present in Acacia seed. S-(2-Carboxyethyl)-L-cysteine can affect the seed’s protein use in rats. S-(2-Carboxyethyl)-L-cysteine suppresses the methionine-induced growth rate, and has a negative effect on the plasma amino acid levels in rats[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vivo]

S-(2-Carboxyethyl)-L-cysteine significantly increases the plasma urea level in rats[1].

[References]

[1]. Falade OS, et al. S-Carboxyethylcysteine (a constituent of Acacia seed) negatively affects casein protein utilization by rats. Nutrition. 2012 Jul;28(7-8):785-92.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
436.5±45.0 °C at 760 mmHg

[ Melting Point ]:
218°C

[ Molecular Formula ]:
C₆H₁₁NO₄S

[ Molecular Weight ]:
193.221

[ Flash Point ]:
217.8±28.7 °C

[ Exact Mass ]:
193.040878

[ PSA ]:
125.92000

[ LogP ]:
0.08

[ Appearance of Characters ]:
solid

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY4300000

CHEMICAL NAME :: Alanine, 3-((2-carboxyethyl)thio)-

CAS REGISTRY NUMBER :: 4033-46-9

BEILSTEIN REFERENCE NO. :: 1725406

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H11-N-O4-S

MOLECULAR WEIGHT :: 193.24

WISWESSER LINE NOTATION :: QVYZ1S2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 520 mg/kg/52W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 15,85,1961

Safety Information

[ RTECS ]:
AY4300000

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%