S-(2-Aminoethyl)-L-cysteine hydrochloride
Names
[ CAS No. ]:
4099-35-8
[ Name ]:
S-(2-Aminoethyl)-L-cysteine hydrochloride
[Synonym ]:
H-Cys(aminoethyl)-OH
H-CYS(ET-NH2)-OH HCL
S-(2-aminoethyl)-L-cysteine monohydrochloride
CYSTEINE(AMINOETHYL)-OH HCL
L-4-thialysine hydrochloride
MFCD00036385
usafxr-43
EINECS 223-862-1
S-(2-Amino-aethyl)-L-cystein,Hydrochlorid
S-(aminoethyl)-L-cysteine hydrochloride
thialysinehydrochloride
S-(2-amino-ethyl)-L-cysteine,hydrochloride
lj226
L-Thialysin Hydrochlorid
H-CYS(AMINOETHYL)-OH HCL
THIALSINE
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[References]
Chemical & Physical Properties
[ Density]:
1.289g/cm3
[ Boiling Point ]:
341.1ºC at 760 mmHg
[ Molecular Formula ]:
C5H13ClN2O2S
[ Molecular Weight ]:
200.68700
[ Flash Point ]:
160.1ºC
[ Exact Mass ]:
200.03900
[ PSA ]:
114.64000
[ LogP ]:
1.29280
[ Index of Refraction ]:
1.57
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HA1690000
- CHEMICAL NAME :
- Cysteine, S-(2-aminoethyl)-, monohydrochloride, L-
- CAS REGISTRY NUMBER :
- 4099-35-8
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C5-H12-N2-O2-S.Cl-H
- MOLECULAR WEIGHT :
- 200.71
- WISWESSER LINE NOTATION :
- Z2S1YZVQ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2155776
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
HA1690000
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Phys. Chem. B 113(36) , 12161-3, (2009)
We demonstrate that the steady state reaction of lysine 5,6-aminomutase with substrate analogue 4-thia-l-lysine generates a radical intermediate, which accumulates in the enzyme to an electron paramag...
Radical triplets and suicide inhibition in reactions of 4-thia-D- and 4-thia-L-lysine with lysine 5,6-aminomutase.Biochemistry 48(34) , 8151-60, (2009)
Lysine 5,6-aminomutase (5,6-LAM) catalyzes the interconversions of D- or L-lysine and the corresponding enantiomers of 2,5-diaminohexanoate, as well as the interconversion of L-beta-lysine and l-3,5-d...
Inhibition of lysine 2,3-aminomutase by the alternative substrate 4-thialysine and characterization of the 4-thialysyl radical intermediate.Arch. Biochem. Biophys. 387(2) , 281-8, (2001)
Lysine 2,3-aminomutase catalyzes the interconversion of L-lysine and L-beta-lysine. 4-Thia-L-lysine (4-thialysine) is an alternative substrate for Lysine 2,3-aminomutase. The organic free radical that...