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L-Cysteine hydrochloride anhydrous

Names

[ CAS No. ]:
52-89-1

[ Name ]:
L-Cysteine hydrochloride anhydrous

[Synonym ]:
EINECS 200-157-7
l-Cys hydrochloride
MFCD00064553
(R)-2-Amino-3-mercaptopropanoic acid hydrochloride
L-Cysteine hydrochloride
Cysteine, hydrochloride, L-
L-Cysteine hydrochloride (1:1)
L-Cysteine, hydrochloride (1:1)
QVYZ1SH &&L or R Form HCl
(R)-(+)-Cysteine hydrochloride
L-Cysteinhydrochlorid(1:1)
L-Cysteine hydrochloride anhydrous

Biological Activity

[Description]:

L-Cysteine hydrochloride is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents and humans[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. McGavigan AK, et al. L-cysteine suppresses ghrelin and reduces appetite in rodents and humans. Int J Obes (Lond). 2015 Mar;39(3):447-55.

Chemical & Physical Properties

[ Boiling Point ]:
293.9ºC at 760 mmHg

[ Melting Point ]:
140-142ºC

[ Molecular Formula ]:
C3H8ClNO2S

[ Molecular Weight ]:
157.619

[ Flash Point ]:
131.5ºC

[ Exact Mass ]:
156.996429

[ PSA ]:
102.12000

[ LogP ]:
0.83040

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA2275000
CHEMICAL NAME :
Cysteine, hydrochloride, L-
CAS REGISTRY NUMBER :
52-89-1
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C3-H7-N-O2-S.Cl-H
MOLECULAR WEIGHT :
157.63
WISWESSER LINE NOTATION :
SH1YZVQ &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
771 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Fibroblast
DOSE/DURATION :
2 gm/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81863 No. of Facilities: 114 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 6426 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81863 No. of Facilities: 492 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 7343 (estimated) No. of Female Employees: 5313 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
HA2275000

[ HS Code ]:
2930909090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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