Amino-PEG6-alcohol

Names

[ Name ]:
Amino-PEG6-alcohol

[Synonym ]:
3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-amino-
17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol
2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Amino-PEG6-alcohol

Biological Activity

[Description]:

Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
388.0±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₂₇NO₆

[ Molecular Weight ]:
281.346

[ Flash Point ]:
188.5±26.5 °C

[ Exact Mass ]:
281.183838

[ PSA ]:
92.40000

[ LogP ]:
-2.80

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.463

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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