N-methyl-L-glutamic acid

Names

[ Name ]:
N-methyl-L-glutamic acid

[Synonym ]:
N-Methyl-DL-glutamic Acid
MFCD00037760
Glutamic acid, N-methyl-, hydrochloride (1:1)
N-Methylglutamic acid hydrochloride (1:1)
2-(Methylamino)pentanedioic acid

Biological Activity

[Description]:

N-Methyl-DL-glutamic acid is a L-Glutamic acid (HY-14608) analog with cytotoxic effects[1][2].

[Related Catalog]:

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Olney JW, et al. Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system. Exp Brain Res. 1971;14(1):61-76.

[2]. Chan PH, et al. Effects of excitatory neurotransmitter amino acids on swelling of rat brain cortical slices. J Neurochem. 1979 Dec;33(6):1309-15.

Chemical & Physical Properties

[ Density]:
1.278g/cm3

[ Boiling Point ]:
330.2ºC at 760mmHg

[ Molecular Formula ]:
C₆H₁₂ClNO₄

[ Molecular Weight ]:
197.617

[ Flash Point ]:
153.5ºC

[ Exact Mass ]:
197.045486

[ PSA ]:
86.63000

[ Index of Refraction ]:
1.491

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Biosynthetic Gene Cluster for the Polyenoyltetramic Acid α-Lipomycin Bihlmayer, C. et al.

Antimicrob. Agents Chemother. 2008 , 2113-2121, (50)

Related Compounds

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