Quercetin 3,4'-dimethyl ether

Names

[ Name ]:
Quercetin 3,4'-dimethyl ether

[Synonym ]:
5,7,3'-Trihydroxy-3,4'-dimethoxyflavone
3',5,7-Trihydroxy-3',4'-dimethoxyflavone
Quercetin 3,4'-dimethyl Ether
5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxy-4H-chromen-4-one
Flavone, 3',5,7-trihydroxy-3,4'-dimethoxy-
3',5,7-Trihydroxy-3,4'-dimethoxyflavone
quercetin-3,4'-dimethyl ether
3,4'-O-dimethylquercetin
MFCD00016927
5,7-Dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-3-methoxy-1-benzopyran-4-one
3',5,7-trihydroxy-3,4'-dimethoxy flavone, Quercetin 3,4'-dimethyl Ether
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxy-
5,5,3'-trihydroxy-3,4'-dimethoxyflavone
3,4'-dimethoxy-5,7-3'-trihydroxyflavone

Biological Activity

[Description]:

Quercetin 3,4′-dimethyl ether (3,4′-Dimethylquercetin) is a dimethoxyflavone can be isolated from Combretum quadrangulare. Quercetin 3,4′-dimethyl ether overcomes TRAIL resistance by enhancing DR5 expression and has anti-tumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Toume K, et al. Cycloartane triterpenes isolated from Combretum quadrangulare in a screening program for death-receptor expression enhancing activity. J Nat Prod. 2011 Feb 25;74(2):249-55.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
607.0±55.0 °C at 760 mmHg

[ Melting Point ]:
229-230ºC

[ Molecular Formula ]:
C₁₇H₁₄O₇

[ Molecular Weight ]:
330.29

[ Flash Point ]:
227.3±25.0 °C

[ Exact Mass ]:
330.073944

[ PSA ]:
109.36000

[ LogP ]:
1.85

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.701

Safety Information

[ HS Code ]:
2914509090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%