RFRP-1(human)

Names

[ Name ]:
RFRP-1(human)

[Synonym ]:
hRFRP-1
human RFamide-related peptide-1

Biological Activity

[Description]:

RFRP-1(human) is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₇H₁₀₁N₁₉O₁₄S

[ Molecular Weight ]:
1428.70000

[ Exact Mass ]:
1427.75000

[ PSA ]:
550.83000

[ LogP ]:
3.27730

Related Compounds

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