311309-25-8
311309-25-8 structure
- Name: RFRP-1(human)
- Chemical Name: MPHSFANLPLRF-amide
- CAS Number: 311309-25-8
- Molecular Formula: C67H101N19O14S
- Molecular Weight: 1428.70000
- Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
- Create Date: 2018-01-30 11:57:32
- Modify Date: 2024-01-09 15:03:41
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RFRP-1(human) is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats.
| Name | MPHSFANLPLRF-amide |
|---|---|
| Synonyms |
hRFRP-1
human RFamide-related peptide-1 |
| Description | RFRP-1(human) is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. |
|---|---|
| Related Catalog |
| Molecular Formula | C67H101N19O14S |
|---|---|
| Molecular Weight | 1428.70000 |
| Exact Mass | 1427.75000 |
| PSA | 550.83000 |
| LogP | 3.27730 |