DL-Alanine

Names

[ CAS No. ]:
302-72-7

[ Name ]:
DL-Alanine

[Synonym ]:
(R,S)-Alanine
(±)-Alanine
Propanoic acid, 2-amino-
(±)-2-Aminopropionic acid
2-amino-propanoic acid
DL-2-aminopropionic acid
α-Aminopropanoic acid
2-Aminopropanoic acid
ZY1&VQ
Alanine,DL
EINECS 206-126-4
Alanine
α-Aminopropionic acid
d,l-alanine
Alanine, DL-
UNII:1FU7983T0U
α-Alanine
2-Aminopropionic Acid
DL-α-Aminopropionic acid
MFCD00064408
H-DL-Ala-OH
DL-2-Aminopropanoic acid
DL-α-Alanine
DL-Aminopropanoic acid
Methyl glycine

Biological Activity

[Description]:

DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

[2]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

[3]. Amrallah AH, et al. Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl-alanine or dl-leucine. Talanta. 1998 Aug;46(4):491-500.

[4]. Yamamoto T, et al. Gustatory reaction time to various sweeteners in human adults. Physiol Behav. 1985 Sep;35(3):411-5.

[5]. Rashid M, et al. Biosynthesis of Self-Dispersed Silver Colloidal Particles Using the Aqueous Extract of P. peruviana for Sensing dl-Alanine[J]. Isrn Nanotechnology, 2014, 2014:1-7.

[6]. Tapper DN, et al. Taste stimuli: a behavioral categorization. Science. 1968 Aug 16;161(3842):708-10.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
212.9±23.0 °C at 760 mmHg

[ Melting Point ]:
272-275ºC

[ Molecular Formula ]:
C₃H₇NO₂

[ Molecular Weight ]:
89.093

[ Flash Point ]:
82.6±22.6 °C

[ Exact Mass ]:
89.047676

[ PSA ]:
63.32000

[ LogP ]:
-0.68

[ Vapour Pressure ]:
0.1±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.460

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
156 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY2980000

CHEMICAL NAME :: DL-Alanine

CAS REGISTRY NUMBER :: 302-72-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C3-H7-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1820 gm/kg/26W-C

TOXIC EFFECTS :: Blood - other changes Biochemical - Metabolism (Intermediary) - lipids including transport

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 37,491,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9124 No. of Facilities: 591 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 8931 (estimated) No. of Female Employees: 5441 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AY2980000

[ HS Code ]:
2936240000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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