NLRP3-IN-11

Names

[ Name ]:
NLRP3-IN-11

Biological Activity

[Description]:

NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of ＜0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Infection

Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR)

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[Target]

NLRP3:<0.3 μM (IC50)

[In Vitro]

NLRP3-IN-11 has biological activity with an IC50 value of ＜0.3 μM in human PBMC NLRP3 assay[1]

[References]

[1]. HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₇ClN₄O₂

[ Molecular Weight ]:
344.80

Related Compounds

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