NLRP3-IN-3

Names

[ Name ]:
NLRP3-IN-3

Biological Activity

[Description]:

NLRP3-IN-3 is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of 1.26 nM in THP1 cells, showing good pharmacokinetic profiles with oral bioavailability.

[References]

1. Sharma R., Iyer P., Agarwal S. Novel Substituted Sulfoximine Compounds. WO/2018/225018.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₅N₅O₃S

[ Molecular Weight ]:
439.534

Related Compounds

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