NLRP3-IN-13

Names

[ Name ]:
NLRP3-IN-13

Biological Activity

[Description]:

NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR)

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[Target]

NLRP3

[References]

[1]. Devita Robert, et al. Benzoxazolones as inhibitors of inflammasomes and their preparation. Patent. WO2022187804.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₅N₃O₃S

[ Molecular Weight ]:
365.41

Related Compounds

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