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RORγt inverse agonist 28

Names

[ CAS No. ]:
2741870-21-1

[ Name ]:
RORγt inverse agonist 28

Biological Activity

[Description]:

RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) [1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR
Research Areas >> Inflammation/Immunology

[References]

[1]. Yaobang Chen, et al. Biaryls as RORγ Modulators. Patent WO2021228215A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H18Cl2F3NO5S

[ Molecular Weight ]:
548.36

Related Compounds