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RORγt inverse agonist 23

Names

[ CAS No. ]:
2230779-18-5

[ Name ]:
RORγt inverse agonist 23

Biological Activity

[Description]:

RORγt inverse agonist 23 is a potent, selective, and orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR
Research Areas >> Inflammation/Immunology

[References]

[1]. Chen L, et al. Discovery of Chromane-6-Sulfonamide Derivative as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist. J Med Chem. 2021 Nov 11;64(21):16106-16131.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H33NO5S

[ Molecular Weight ]:
471.61

Related Compounds