o-Hydroxy Atorvastatin D5 Calcium Salt

Names

[ Name ]:
o-Hydroxy Atorvastatin D5 Calcium Salt

[Synonym ]:
[2H5]-o-Hydroxyatorvastatin calcium salt
o-Hydroxy Atorvastatin D5 Calcium Salt

Biological Activity

[Description]:

Ortho-hydroxy atorvastatin-d5 calciumis the deuterium labeledOrtho-hydroxy atorvastatin(HY-144577)[1]. Ortho-hydroxy atorvastatin is the metabolic of Atorvastatin (HY-B0589)[2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Zhou Y, et al. Development and validation of a liquid chromatography-tandem mass spectrometry method for simultaneous determination of amlodipine, atorvastatin and its metabolites ortho-hydroxy atorvastatin and para-hydroxy atorvastatin in human plasma and its application in a bioequivalence study. J Pharm Biomed Anal. 2013 Sep;83:101-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₃₀D₅FN₂O_6.1/₂Ca

[ Molecular Weight ]:
599.71

[ Exact Mass ]:
1186.442749

[ PSA ]:
138.34000

[ LogP ]:
6.84140

Related Compounds

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