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2-Hydroxy atorvastatin calcium salt

Names

[ CAS No. ]:
265989-46-6

[ Name ]:
2-Hydroxy atorvastatin calcium salt

[Synonym ]:
2-Hydroxy atorvastatin calcium salt

Biological Activity

[Description]:

2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM.

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Borek-Dohalský V, et al. Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study. Anal Bioanal Chem. 2006 Sep;386(2):275-85.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H34CaFN2O6

[ Molecular Weight ]:
613.70900

[ Exact Mass ]:
613.20300

[ PSA ]:
138.34000

[ LogP ]:
6.84140

Related Compounds