265989-47-7

265989-47-7 structure

Name: o-Hydroxy Atorvastatin D5 Calcium Salt
Chemical Name: calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-(2,3,4,5,6-pentadeuteriophenyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
CAS Number: 265989-47-7
Molecular Formula: C₃₃H₃₀D₅FN₂O_6.1/₂Ca
Molecular Weight: 599.71
Catalog: Research Areas Others
Create Date: 2017-02-22 14:39:15
Modify Date: 2024-01-02 16:29:55
Ortho-hydroxy atorvastatin-d5 calciumis the deuterium labeledOrtho-hydroxy atorvastatin(HY-144577)[1]. Ortho-hydroxy atorvastatin is the metabolic of Atorvastatin (HY-B0589)[2].

Name	calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-(2,3,4,5,6-pentadeuteriophenyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
Synonyms	[2H5]-o-Hydroxyatorvastatin calcium salt o-Hydroxy Atorvastatin D5 Calcium Salt

Description	Ortho-hydroxy atorvastatin-d5 calciumis the deuterium labeledOrtho-hydroxy atorvastatin(HY-144577)[1]. Ortho-hydroxy atorvastatin is the metabolic of Atorvastatin (HY-B0589)[2].
Related Catalog	Research Areas >> Others
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Zhou Y, et al. Development and validation of a liquid chromatography-tandem mass spectrometry method for simultaneous determination of amlodipine, atorvastatin and its metabolites ortho-hydroxy atorvastatin and para-hydroxy atorvastatin in human plasma and its application in a bioequivalence study. J Pharm Biomed Anal. 2013 Sep;83:101-7.