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KRAS G12C inhibitor 28

Names

[ CAS No. ]:
2649004-88-4

[ Name ]:
KRAS G12C inhibitor 28

Biological Activity

[Description]:

KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRas G12C:57 nM (IC50)


[References]

[1]. Don Zhang, et al. Phosphorus derivatives as kras inhibitors. WO2021113595A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H36F2N5O4P

[ Molecular Weight ]:
635.64


Related Compounds