MC-Val-Cit-PAB-DX8951

Names

[ Name ]:
MC-Val-Cit-PAB-DX8951

Biological Activity

[Description]:

MC-Val-Cit-PAB-DX8951 is a drug-linker conjugate for ADC. MC-Val-Cit-PAB-DX8951 is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker.

[Related Catalog]:

Research Areas >> Cancer

[Target]

Camptothecins

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Anish Thomas, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₃H₆₀FN₉O₁₂

[ Molecular Weight ]:
1034.10

MC-Val-Cit-PAB-DX8951

Names

Biological Activity

Chemical & Physical Properties

Related Compounds