Dantrolene sodium

Names

[ Name ]:
Dantrolene sodium

[Synonym ]:
Sodium 3-[(E)-{[5-(4-nitrophenyl)-2-furyl]methylene}amino]-2,5-dioxoimidazolidin-1-ide hydrate (2:2:7)
Dantrolene, Sodium Salt Hemiheptahydrate
Dantrolene sodium
2,4-Imidazolidinedione, 1-[[(1E)-[5-(4-nitrophenyl)-2-furanyl]methylene]amino]-, sodium salt, hydrate (2:2:7)
MFCD00079130
Dantrolene (sodium hemiheptahydrate)

Biological Activity

[Description]:

Dantrolene sodium hemiheptahydrate is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction. Dantrolene sodium hemiheptahydrate is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm.

[Related Catalog]:

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Boiling Point ]:
544.5ºC at 760mmHg

[ Melting Point ]:
>230ºC

[ Molecular Formula ]:
C₁₄H₁₇N₄NaO_8.5

[ Molecular Weight ]:
400.30

[ Flash Point ]:
283.1ºC

[ PSA ]:
318.71000

[ LogP ]:
2.97810

[ Vapour Pressure ]:
1.09E-12mmHg at 25°C

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
MU3875000

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%