Akt Inhibitor X

Names

[ CAS No. ]:
201788-90-1

[ Name ]:
Akt Inhibitor X

[Synonym ]:
Akt Inhibitor X
10-DEBC HYDROCHLORIDE

Biological Activity

[Description]:

10-DEBC is a selective Akt inhibitor. 10-DEBC shows strong inhibitory activity against Moloney murine leukemia virus (Pim) kinase-1 (IC50=1.28 μM)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> Pim

[Target]

1.28 μM (Pim) [1]

[References]

[1]. Li, W., et al. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors. Med. Chem. Commun. 2014;5(4):507–511.

Chemical & Physical Properties

[ Boiling Point ]:
490.9ºC at 760mmHg

[ Molecular Formula ]:
C₂₀H₂₆Cl₂N₂O

[ Molecular Weight ]:
381.33900

[ Flash Point ]:
250.7ºC

[ Exact Mass ]:
380.14200

[ PSA ]:
15.71000

[ LogP ]:
6.57280

[ Vapour Pressure ]:
5.08E-10mmHg at 25°C

Akt Inhibitor X

Names

Biological Activity

Chemical & Physical Properties

Related Compounds