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Tipifarnib (S enantiomer)

Names

[ CAS No. ]:
192185-71-0

[ Name ]:
Tipifarnib (S enantiomer)

[Synonym ]:
tipifarnib
Tipifarnib (S enantiomer)

Biological Activity

[Description]:

Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase
Research Areas >> Cancer

[Related Small Molecules]

Tipifarnib (R115777) | FTI-277 (hydrochloride) | L-778123 (hydrochloride) | Lonafarnib | BMS 214662 | FTI-276 trifluoroacetate salt | LNK754 | Prenyl-IN-1 | RPR107393 free base | YM-53601 free base

Chemical & Physical Properties

[ Molecular Formula ]:
C27H22Cl2N4O

[ Molecular Weight ]:
489.39600

[ Exact Mass ]:
488.11700

[ PSA ]:
65.84000

[ LogP ]:
6.19670

[ Storage condition ]:
2-8℃

Related Compounds