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Nazartinib S-enantiomer

Names

[ CAS No. ]:
1508256-20-9

[ Name ]:
Nazartinib S-enantiomer

[Synonym ]:
N-(7-Chloro-1-{(3S)-1-[(2E)-4-(dimethylamino)-2-butenoyl]-3-azepanyl}-1H-benzimidazol-2-yl)-2-methylisonicotinamide
4-Pyridinecarboxamide, N-[7-chloro-1-[(3S)-1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]hexahydro-1H-azepin-3-yl]-1H-benzimidazol-2-yl]-2-methyl-
EGF816 (S-enantiomer)

Biological Activity

[Description]:

Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR inhibitor.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Others

[References]

[1]. Gerald Lelais, et al. Compounds and compositions for modulating egfr activity. WO 2013184757A1.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C26H31ClN6O2

[ Molecular Weight ]:
495.016

[ Exact Mass ]:
494.219696

[ LogP ]:
3.23

[ Index of Refraction ]:
1.643

Related Compounds

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