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KIN-1408

Names

[ CAS No. ]:
1903800-11-2

[ Name ]:
KIN-1408

Biological Activity

[Description]:

KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway.Target: KIN1408 activate IRF3 through MAVS, thereby inhibiting infection by viruses of the families Flaviviridae (West Nile virus, dengue virus and hepatitis C virus), Filoviridae (Ebola virus), Orthomyxoviridae (influenza A virus), Arenaviridae (Lassa virus) and Paramyxoviridae (respiratory syncytial virus, Nipah virus) .

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HCV
Research Areas >> Infection

[References]

[1]. Green RR, et al. Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway. Genom Data. 2016 Feb 1;7:290-2.


[Related Small Molecules]

Asunaprevir | Sofosbuvir | Simeprevir | Ledipasvir | paritaprevir | Artemisinin | Elbasvir | NIM811 | MK-5172 | velpatasvir | Ombitasvir | Danoprevir (ITMN-191) | Glecaprevir | Celgosivir (hydrochloride) | Alisporivir

Chemical & Physical Properties

[ Molecular Formula ]:
C25H19F2N3O3S

[ Molecular Weight ]:
479.5

[ Storage condition ]:
2-8℃

[ Water Solubility ]:
DMSO: ≥ 39 mg/mL

Related Compounds