5-AAM-2-CP

Names

[ Name ]:
5-AAM-2-CP

[Synonym ]:
2-chloro-5-acetaminomethylpyridine

Biological Activity

[Description]:

5-AAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is a nAChR agonist[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

Research Areas >> Neurological Disease

[In Vivo]

5-AAM-2-CP (5-(N-acetylaminomethyl)-2-chloropyridine) hydrolyzed product of N-desmethylacetamiprid Acetamiprid can be metabolized to 5-AAM-2-CP in both blood and urine[1].

[References]

[1]. Tadashi Yamamuro, et al. Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth-assisted extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 15;969:85-94.

[2]. Terayama H, et al. Effect of acetamiprid on the immature murine testes. Int J Environ Health Res. 2018 Dec;28(6):683-696.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₉ClN₂O

[ Molecular Weight ]:
184.62300

[ Exact Mass ]:
184.04000

[ PSA ]:
41.99000

[ LogP ]:
1.76200

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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