PNU 96415E

Names

[ CAS No. ]:
170856-41-4

[ Name ]:
PNU 96415E

[Description]:

PNU-96415E is a selective D4/5-HT2A antagonist. PNU-96415E may have potential antipsychotic efficacy[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

D4 Receptor

5-HT2A Receptor

[In Vivo]

PNU-96415E blockes 5-HTP-induced bead twitches in mice and stereotypic behaviours produced by high doses of amphetamine and methylphenidate[1].

[References]

[ Molecular Formula ]:
C₂₁H₂₇Cl₂FN₂O

[ Molecular Weight ]:
413.35600

[ Exact Mass ]:
412.14800

[ PSA ]:
15.71000

[ LogP ]:
5.25870