Pantoprazole Sodium Hydrate

Names

[ Name ]:
Pantoprazole Sodium Hydrate

[Synonym ]:
6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt hydrate (2:2:3)
Pantoprazole (sodium hydrate)

Biological Activity

[Description]:

Pantoprazole sodium hydrate is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.IC50 value:Target: proton pump inhibitor

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump

Research Areas >> Others

[References]

[1]. http://www.drugbank.ca/drugs/DB00213

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₅F₂N₃O₄S_.3/₂H₂O_.Na

[ Molecular Weight ]:
433.38

[ Water Solubility ]:
Freely soluble in water and in ethanol (96 per cent), practically insoluble in hexane.

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

Articles

Efficacy of rhubarb combined with early enteral nutrition for the treatment of severe acute pancreatitis: a randomized controlled trial.

Scand. J. Gastroenterol. 49(11) , 1375-84, (2014)

To investigate the effect of rhubarb combined with early enteral nutrition (EEN) on the gastrointestinal function, disease severity and systemic inflammation in patients with severe acute pancreatitis...