AD-35
Names
[ CAS No. ]:
1531586-58-9
[ Name ]:
AD-35
Biological Activity
[Description]:
A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.
[References]
References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE)
Chemical & Physical Properties
[ Molecular Formula ]:
C24H27N3O3
[ Molecular Weight ]:
405.498