AD-35 phosphate

Names

[ Name ]:
AD-35 phosphate

Biological Activity

[Description]:

A donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates; markedly attenuates Aβ25-35 injection-induced astrocyte activation, pro-inflammatory cytokines TNF-α and IL-1β release, and memory deficits in vivo; orally active.

[References]

References 1. Li L, et al. J Alzheimers Dis. 2017;56(4):1403-1417. View Related Products by Target Acetylcholinesterase (AChE)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₇N₃O_3.H₃O₄P

[ Molecular Weight ]:
503.485

Related Compounds

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