FGIN-1-43

Names

[ Name ]:
FGIN-1-43

[Synonym ]:
FGIN-1-43
Tocris-0659

Biological Activity

[Description]:

FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids). FGIN 1-43 enhances the transmission of GABA by inducing the production of neurosteroids, which can be used for research on anti-anxiety[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Guillon J, et al. Synthesis and preliminary behavioural evaluation in mice of new 3-aryl-3-pyrrol-1-ylpropanamides, analogues of FGIN-1-27 and FGIN-1-43. J Pharm Pharmacol. 2001 Nov;53(11):1561-8.

Chemical & Physical Properties

[ Density]:
1.143g/cm3

[ Boiling Point ]:
648.5ºC at 760 mmHg

[ Molecular Formula ]:
C₂₈H₃₆Cl₂N₂O

[ Molecular Weight ]:
487.50

[ Flash Point ]:
346ºC

[ Exact Mass ]:
486.22000

[ PSA ]:
36.10000

[ LogP ]:
8.67340

[ Vapour Pressure ]:
1.05E-16mmHg at 25°C

[ Index of Refraction ]:
1.579

[ Storage condition ]:
-20°C

FGIN-1-43

Names

Biological Activity

Chemical & Physical Properties

Related Compounds