Azido-PEG5-acid

Names

[ Name ]:
Azido-PEG5-acid

[Synonym ]:
1-Azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid
3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-
MFCD22056306

Biological Activity

[Description]:

Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin (HY-16560)).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

Research Areas >> Inflammation/Immunology

[Target]

Non-cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Zolotarskaya OY, et al. Click synthesis of a polyamidoamine dendrimer-based camptothecin prodrug. RSC Adv. 2015;5(72):58600-58608. Epub 2015 Jun 29.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₂₅N₃O₇

[ Molecular Weight ]:
379.406

[ Exact Mass ]:
379.195465

[ LogP ]:
-1.78

[ Storage condition ]:
2-8°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.