T.cruzi-IN-1
Names
[ CAS No. ]:
1350920-22-7
[ Name ]:
T.cruzi-IN-1
Biological Activity
[Description]:
T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease[1].
[Related Catalog]:
[Target]
IC50: 8 nM (Trypanosoma cruzi)[1]
[In Vitro]
T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C22H25F3N2O
[ Molecular Weight ]:
390.44200
[ Exact Mass ]:
390.19200
[ PSA ]:
23.55000
[ LogP ]:
4.51390
[ Storage condition ]:
-20℃