ICI 199,441 hydrochloride

Names

[ Name ]:
ICI 199,441 hydrochloride

[Synonym ]:
ici 199,441
ici 199,441 hydrochloride

[Description]:

ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

[In Vivo]

ICI 199441 (Wistar rats, 0.1 mg/kg, IV, once) administered 15 min before ischemia produces a potent antiarrhythmic effect[1].

[References]

[ Boiling Point ]:
532.8ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₂₅Cl₃N₂O

[ Molecular Weight ]:
427.80

[ Flash Point ]:
276ºC

[ Exact Mass ]:
426.10300

[ PSA ]:
23.55000

[ LogP ]:
5.57130

[ Vapour Pressure ]:
1.97E-11mmHg at 25°C