tilmicosin

Names

[ Name ]:
tilmicosin

[Synonym ]:
Micotil 300
pulmotil
Antibiotic EL 870
EL 870
MFCD00864842
Micotil

Biological Activity

[Description]:

Tilmicosin is a macrolide antibiotic, is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Infection

[References]

[1]. Micotil 300 New Animal Drug Application

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
926.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₆H₈₀N₂O₁₃

[ Molecular Weight ]:
869.133

[ Flash Point ]:
514.2±34.3 °C

[ Exact Mass ]:
868.566040

[ PSA ]:
186.15000

[ LogP ]:
4.95

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.545

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

Articles

Extraction of trace tilmicosin in real water samples using ionic liquid-based aqueous two-phase systems.

Water Sci. Technol. 67(8) , 1671-7, (2013)

The effective method of ionic liquid-based aqueous two-phase extraction, which involves ionic liquid (IL) (1-butyl-3-methyllimidazolium chloride, [C4mim]Cl) and inorganic salt (K2HPO4) coupled with hi...

Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases.

Vet. Microbiol. 150(1-2) , 203-6, (2011)

Limited data regarding the susceptibility of Actinobacillus pleuropneumoniae to antimicrobials has been published during recent years. Accordingly, the aim of the present study was to investigate the ...

Kinetics and intrapulmonary disposition of tilmicosin after single and repeated oral bolus administrations to rabbits.

Vet. Res. Commun. 34 Suppl 1 , S69-72, (2010)

Tilmicosin (TIM, Pulmotil) was administered to eight rabbits by oral gavage at a dose of 12.5 mg/kg body weight for 2, 5, and 7 days, and its plasma kinetics and intrapulmonary disposition were invest...