MMP-2 Inhibitor I

Names

[ Name ]:
MMP-2 Inhibitor I

[Synonym ]:
N-hydroxyoleamide
N-Hydroxyoleic amide
9-Octadecenamide,N-hydroxy-,(9Z)
N-Hydroxy-oleamid
Einecs 233-728-4
cis-9-cctadecenoyl-N-hydroxylamide
Oleoylhydroxamic acid
Oelsaeure-hydroxyamid
Oleohydroxamsaeure
(9Z)-9-Octadecenehydroxamic acid
(Z)-N-Hydroxy-9-octadecenamide
N-Hydroxyoleylamide
N-Hydroxy-9-octadecenamide
oleohydroxamic acid

Biological Activity

[Description]:

MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a Ki of 1.7 μM[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[Target]

MMP-2:1.7 μM (Ki)

[In Vitro]

MMP-2 inhibitor I (OA-Hy；5 μM；预处理 30 分钟) 明显抑制 R1881 增强的 LNCaP 细胞迁移[1]。 Cell Invasion Assay[1] Cell Line: LNCaP cells Concentration: 5 μM Incubation Time: Pretreated for 30 min and then co-incubated for 48 h Result: R1881-enhanced LNCaP cell migration was clearly suppressed.

Chemical & Physical Properties

[ Density]:
0.921g/cm3

[ Molecular Formula ]:
C₁₈H₃₅NO₂

[ Molecular Weight ]:
297.47600

[ Exact Mass ]:
297.26700

[ PSA ]:
49.33000

[ LogP ]:
5.92020

[ Index of Refraction ]:
1.473

Safety Information

[ HS Code ]:
2924199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%