186347-28-4

• 常用中文名：4-氰基-4-邻甲苯哌啶-1-羧酸叔丁酯
• 常用英文名：1-BOC-4-CYANO-4-(2-METHYLPHENYL)-PIPERIDINE
• CAS号：186347-28-4
• 分子式：C₁₈H₂₄N₂O₂
• 分子量：300.39500
• 发布时间：2018-12-16 17:15:04
• 更新时间：2024-01-09 11:44:43

名称

• 中文名: 4-氰基-4-邻甲苯哌啶-1-羧酸叔丁酯
• 英文名: tert-butyl 4-cyano-4-(2-methylphenyl)piperidine-1-carboxylate

物化性质

• 分子式: C₁₈H₂₄N₂O₂
• 分子量: 300.39500
• 精确质量: 300.18400
• PSA: 53.33000
• LogP: 3.72518

合成路线

118753-70-1 22364-68-7 ~33% 186347-28-4

文献：SCHERING CORPORATION; BOGEN, Stephane, L.; MA, Yao; WANG, Yaolin; LAHUE, Brian Robert; NAIR, Latha, G.; SHIZUKA, Manami; VOSS, Matthew Ernst; KIROVA-SNOVER, Margarita; PAN, Weidong; TIAN, Yuan; KULKARNI, Bheemashankar, A.; GIBEAU, Craig, R.; LIU, Yuan; SCAPIN, Giovanna; RINDGEN, Diane; DOLL, Ronald, J.; GUZI, Timothy, J.; HICKLIN, Danny, J.; NOMEIR, Amin; SEIDEL-DUGAN, Cynthia; SHIPPS, Gerald, W., Jr.; MACCOSS, Malcolm Patent: WO2011/46771 A1, 2011 ; Location in patent: Page/Page column 156 ; WO 2011/046771 A1

24424-99-5 ~% 186347-28-4

文献：SCHERING CORPORATION; BOGEN, Stephane, L.; MA, Yao; WANG, Yaolin; LAHUE, Brian Robert; NAIR, Latha, G.; SHIZUKA, Manami; VOSS, Matthew Ernst; KIROVA-SNOVER, Margarita; PAN, Weidong; TIAN, Yuan; KULKARNI, Bheemashankar, A.; GIBEAU, Craig, R.; LIU, Yuan; SCAPIN, Giovanna; RINDGEN, Diane; DOLL, Ronald, J.; GUZI, Timothy, J.; HICKLIN, Danny, J.; NOMEIR, Amin; SEIDEL-DUGAN, Cynthia; SHIPPS, Gerald, W., Jr.; MACCOSS, Malcolm Patent: WO2011/46771 A1, 2011 ; WO 2011/046771 A1