614730-96-0

• 常用中文名：4-氰基-4-(羟基甲基)哌啶-1-羧酸叔丁酯
• 常用英文名：2-Methyl-2-propanyl 4-cyano-4-(hydroxymethyl)-1-piperidinecarboxylate
• CAS号：614730-96-0
• 分子式：C₁₂H₂₀N₂O₃
• 分子量：240.299
• 发布时间：2018-12-21 09:28:43
• 更新时间：2024-01-10 19:00:26

名称

• 中文名: 4-氰基-4-(羟基甲基)哌啶-1-羧酸叔丁酯
• 英文名: tert-butyl 4-cyano-4-(hydroxymethyl)piperidine-1-carboxylate
• 英文别名: 2-Methyl-2-propanyl 4-cyano-4-(hydroxymethyl)-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 4-cyano-4-(hydroxymethyl)-, 1,1-dimethylethyl ester

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 382.3±27.0 °C at 760 mmHg
• 分子式: C₁₂H₂₀N₂O₃
• 分子量: 240.299
• 闪点: 185.0±23.7 °C
• 精确质量: 240.147400
• PSA: 73.56000
• LogP: 0.23
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.510
• 储存条件: 室温，密封，干燥

安全

• 海关编码: 2933399090

合成路线

162686-53-5 24424-99-5 ~% 614730-96-0

文献：ASTRAZENECA AB Patent: WO2007/30061 A1, 2007 ; Location in patent: Page/Page column 92-93 ; WO 2007/030061 A1

1016258-66-4 ~82% 614730-96-0

文献：Giordanetto, Fabrizio; Wallberg, Andreas; Knerr, Laurent; Selmi, Nidhal; Ullah, Victoria; Thorstensson, Fredrik; Lindelo, Asa; Karlsson, Staffan; Nikitidis, Grigorios; Llinas, Antonio; Wang, Qing-Dong; Lindqvist, Anders; Hoegberg, Agot; Lindhardt, Emma; Astrand, Annika; Duker, Goeran Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 119 - 124

50-00-0 91419-52-2 ~37% 614730-96-0

文献：Gilbert, Eric J.; Zhou, Guowei; Wong, Michael K.C.; Tong, Ling; Shankar, Bandarpalle B.; Huang, Chunli; Kelly, Joseph; Lavey, Brian J.; McCombie, Stuart W.; Chen, Lei; Rizvi, Razia; Dong, Youhao; Shu, Youheng; Kozlowski, Joseph A.; Shih, Neng-Yang; Hipkin, R. William; Gonsiorek, Waldemar; Malikzay, Asra; Lunn, Charles A.; Favreau, Len; Lundell, Daniel J. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 2 p. 608 - 611

91419-52-2 ~% 614730-96-0

文献：Giordanetto, Fabrizio; Wallberg, Andreas; Knerr, Laurent; Selmi, Nidhal; Ullah, Victoria; Thorstensson, Fredrik; Lindelo, Asa; Karlsson, Staffan; Nikitidis, Grigorios; Llinas, Antonio; Wang, Qing-Dong; Lindqvist, Anders; Hoegberg, Agot; Lindhardt, Emma; Astrand, Annika; Duker, Goeran Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 119 - 124

4395-98-6 ~% 614730-96-0

文献：Giordanetto, Fabrizio; Wallberg, Andreas; Knerr, Laurent; Selmi, Nidhal; Ullah, Victoria; Thorstensson, Fredrik; Lindelo, Asa; Karlsson, Staffan; Nikitidis, Grigorios; Llinas, Antonio; Wang, Qing-Dong; Lindqvist, Anders; Hoegberg, Agot; Lindhardt, Emma; Astrand, Annika; Duker, Goeran Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 119 - 124

24424-99-5 ~% 614730-96-0

文献：Giordanetto, Fabrizio; Wallberg, Andreas; Knerr, Laurent; Selmi, Nidhal; Ullah, Victoria; Thorstensson, Fredrik; Lindelo, Asa; Karlsson, Staffan; Nikitidis, Grigorios; Llinas, Antonio; Wang, Qing-Dong; Lindqvist, Anders; Hoegberg, Agot; Lindhardt, Emma; Astrand, Annika; Duker, Goeran Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 119 - 124

上下游产品

上游产品  6
162686-53-5 24424-99-5 1016258-66-4 50-00-0
91419-52-2 4395-98-6
下游产品  0

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%