中文名 | (+)-2-蒈烯 |
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英文名 | (+)-2-carene |
中文别名 |
蒈烯
(1S)-3,7,7-三甲基二环[4.1.0]庚-2-烯 |
英文别名 |
EINECS 224-792-4
MFCD00066416 |
描述 | (+)-2-Carene 是 2-Carene 的异构体。2-Carene 是一种天然存在的双环单萜烯,具有抗炎、抗菌、抗氧化、抗肿瘤和抗过敏活性,以及神经保护、心脏保护和肝脏保护作用。(+)-2-Carene 可经过多重异构化途径获得。 |
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相关类别 | |
参考文献 |
密度 | 0.879g/cm3 |
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沸点 | 167.5ºC at 760mmHg |
熔点 | 25°C (estimate) |
分子式 | C10H16 |
分子量 | 136.23400 |
闪点 | 38.3ºC |
精确质量 | 136.12500 |
LogP | 2.99870 |
折射率 | n20/D 1.476(lit.) |
储存条件 | 避光,通风干燥处,密封保存 |
稳定性 | 常温常压下稳定,易燃,具有刺激性。避免吸入本品蒸气,避免与眼睛、皮肤接触。 |
分子结构 | 1、 摩尔折射率:43.96 2、 摩尔体积(cm3/mol):154.9 3、 等张比容(90.2K):347.5 4、 表面张力(dyne/cm):25.3 5、 介电常数(F/m):2.58 6、 极化率(10-24cm3):17.42 |
计算化学 | 1、 疏水参数计算参考值(XlogP):4.2 2、 氢键供体数量:0 3、 氢键受体数量:0 4、 可旋转化学键数量:0 5、 拓扑分子极性表面积(TPSA):0 6、 重原子数量:10 7、 表面电荷:0 8、 复杂度:186 9、 同位素原子数量:0 10、 确定原子立构中心数量:2 11、 不确定原子立构中心数量:0 12、 确定化学键立构中心数量:0 13、 不确定化学键立构中心数量:0 14、 共价键单元数量:1 |
更多 | 1. 性状:无色油状液体,有松节油的气味。 2. 密度(g/ml,30/30°C):0.8586
3. 相对密度(20℃,4℃):0.8601 4. 熔点(ºC):不确定 5. 沸点(ºC,常压):167 6. 沸点(ºC,5mmHg):不确定 7. 折射率:1.4745 8. 常温折射率(n25):1.471730 9. 比旋光度(º):+7.7 10. 自燃点或引燃温度(ºC):不确定11. 蒸气压(kPa,20ºC):不确定 12. 饱和蒸气压(kPa,60ºC):不确定 13. 燃烧热(KJ/mol):不确定 14. 临界温度(ºC):不确定 15. 临界压力(KPa):不确定 16. 油水(辛醇/水)分配系数的对数值:不确定 17. 爆炸上限(%,V/V):不确定 18. 爆炸下限(%,V/V):不确定 19. 溶解性:溶于乙醚、丙酮、苯、乙酸和油类,不溶于水。 |
SECTION 1: Identification of the substance/mixture and of the company/undertaking Product identifiers Product name: (+)-2-Carene REACH No.: A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No.: 4497-92-1 SECTION 2: Hazards identification Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Flammable liquids (Category 3), H226 For the full text of the H-Statements mentioned in this Section, see Section 16. Classification according to EU Directives 67/548/EEC or 1999/45/EC R10 For the full text of the R-phrases mentioned in this Section, see Section 16. Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal wordWarning Hazard statement(s) Flammable liquid and vapour. Precautionary statement(s)none Supplemental Hazardnone Statements Other hazards - none SECTION 3: Composition/information on ingredients Substances Formula: C10H16 Molecular Weight: 136,23 g/mol CAS-No.: 4497-92-1 EC-No.: 224-792-4 No components need to be disclosed according to the applicable regulations. For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16 SECTION 4: First aid measures Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 Indication of any immediate medical attention and special treatment needed no data available SECTION 5: Firefighting measures Extinguishing media Suitable extinguishing media For small (incipient) fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large fires, apply water from as far as possible. Use very large quantities (flooding) of water applied as a mist or spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Special hazards arising from the substance or mixture Carbon oxides Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information Use water spray to cool unopened containers. SECTION 6: Accidental release measures Personal precautions, protective equipment and emergency procedures Avoid breathing vapours, mist or gas. Remove all sources of ignition. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Reference to other sections For disposal see section 13. SECTION 7: Handling and storage Precautions for safe handling Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated SECTION 8: Exposure controls/personal protection Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0,4 mm Break through time: 480 min Splash contact Material: Nature latex/chloroprene Minimum layer thickness: 0,6 mm Break through time: 30 min test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection impervious clothing, Flame retardant antistatic protective clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. SECTION 9: Physical and chemical properties Information on basic physical and chemical properties a) AppearanceForm: clear, liquid Colour: colourless b) Odourno data available c) Odour Thresholdno data available d) pHno data available e) Melting point/freezingno data available point f) Initial boiling point and 167 - 168 °C boiling range g) Flash point38 °C - closed cup h) Evapouration rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerno data available flammability or explosive limits k) Vapour pressureno data available l) Vapour densityno data available m) Relative density0,862 g/mL at 25 °C n) Water solubilityno data available o) Partition coefficient: n- no data available octanol/water p) Auto-ignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesno data available t) Oxidizing propertiesno data available Other safety information no data available SECTION 10: Stability and reactivity Reactivity no data available Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions no data available Conditions to avoid Heat, flames and sparks. Incompatible materials Strong oxidizing agents Hazardous decomposition products Other decomposition products - no data available In the event of fire: see section 5 SECTION 11: Toxicological information Information on toxicological effects Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitisation no data available Germ cell mutagenicity no data available Carcinogenicity IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. SECTION 12: Ecological information Toxicity no data available Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted Other adverse effects no data available SECTION 13: Disposal considerations Waste treatment methods Product Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging Dispose of as unused product. SECTION 14: Transport information UN number ADR/RID: 2319IMDG: 2319IATA: 2319 UN proper shipping name ADR/RID: TERPENE HYDROCARBONS, N.O.S. IMDG: TERPENE HYDROCARBONS, N.O.S. IATA:Terpene hydrocarbons, n.o.s. Transport hazard class(es) ADR/RID: 3IMDG: 3IATA: 3 Packaging group ADR/RID: IIIIMDG: IIIIATA: III Environmental hazards ADR/RID: noIMDG Marine pollutant: noIATA: no Special precautions for user no data available SECTION 15: Regulatory information This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture no data available Chemical Safety Assessment For this product a chemical safety assessment was not carried out SECTION 16 - ADDITIONAL INFORMATION N/A |
毒理学数据: 对皮肤及黏膜具有局部刺激作用;长时间接触本品可导致过敏性皮炎乃至慢性肺功能损伤[9]。当摄入量达5000mg/m3时,可引起豚鼠支气管缩小[10]。 生态学数据: 通常对水是不危害的,若无政府许可,勿将材料排入周围环境
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符号 |
GHS02 |
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信号词 | Warning |
危害声明 | H226 |
个人防护装备 | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
危害码 (欧洲) | Xi: Irritant; |
风险声明 (欧洲) | 10 |
安全声明 (欧洲) | 16-26-36/37/39-45 |
危险品运输编码 | UN 3295 3/PG 3 |
海关编码 | 2902199090 |
上游产品 8 | |
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下游产品 6 | |
海关编码 | 2902199090 |
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中文概述 | 2902199090 其他环烷烃、环烯烃及环萜烯。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:2.0%。普通关税:30.0% |
申报要素 | 品名, 成分含量 |
Summary | 2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |