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磺胺乙氧嗪

磺胺乙氧嗪用途

Sulfaethoxypyridazine 是一种磺胺类抗菌剂 (antibacterial)。Sulfaethoxypyridazine是一种磺酰胺,在兽药中用作饲料。

磺胺乙氧嗪名称

[ CAS 号 ]:
963-14-4

[ 中文名 ]:
磺胺乙氧嗪

[ 英文名 ]:
Sulfaethoxypyridazine

[中文别名 ]:

磺胺乙氧基哒嗪

[英文别名 ]:

Cysul
EINECS 213-514-7
3-Sulfanilylamino-6-aethoxy-pyridazin
6-Aethoxy-3-sulfanilamino-pyridazin
SULFAETHOXYPYRIDAZINE

磺胺乙氧嗪生物活性

[ 描述 ]:

Sulfaethoxypyridazine 是一种磺胺类抗菌剂 (antibacterial)。Sulfaethoxypyridazine是一种磺酰胺,在兽药中用作饲料。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[ 靶点 ]

Antibacterial[1]

[体内研究]

以800、1600和3200 ppm的日粮水平给大鼠喂饲长效磺胺磺胺乙氧基哒嗪,可导致23周前出现典型的晶状体混浊。狗每天口服30、67和150毫克/公斤,导致14周内出现类似的白内障[1]。

[参考文献]

[1]. Ribelin WE, et al. Development of cataracts in dogs and rats from prolonged feeding of sulfaethoxypyridazine. Toxicol Appl Pharmacol. 1967 May;10(3):557-64.

磺胺乙氧嗪物理化学性质

[ 密度 ]:
1.416g/cm3

[ 沸点 ]:
565.9ºC at 760mmHg

[ 熔点 ]:
182-184ºC

[ 分子式 ]:
C₁₂H₁₄N₄O₃S

[ 分子量 ]:
294.33000

[ 闪点 ]:
296ºC

[ 精确质量 ]:
294.07900

[ PSA ]:
115.58000

[ LogP ]:
2.99330

[ 折射率 ]:
1.632

磺胺乙氧嗪MSDS

磺胺乙氧嗪毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WO9410000

CHEMICAL NAME :: Sulfanilamide, N(sup 1)-(6-ethoxy-3-pyridazinyl)-

CAS REGISTRY NUMBER :: 963-14-4

BEILSTEIN REFERENCE NO. :: 0286161

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H14-N4-O3-S

MOLECULAR WEIGHT :: 294.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 16240 mg/kg/29W-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in pituitary weight Endocrine - changes in thyroid weight

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 30450 mg/kg/29W-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in thyroid weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967

磺胺乙氧嗪安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
WO9410000

[ 海关编码 ]:
2935009090

磺胺乙氧嗪合成路线

磺胺乙氧嗪海关

[ 海关编码 ]: 2935009090

[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:35.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

磺胺乙氧嗪文献

Analysis of sulfonamides, trimethoprim, fluoroquinolones, quinolones, triphenylmethane dyes and methyltestosterone in fish and shrimp using liquid chromatography-mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 972 , 38-47, (2014)

A liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method is described for the detection and identification of 26 veterinary drugs in fish and other aquaculture products. The analyt...

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