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原黄素盐酸盐

原黄素盐酸盐名称

[ CAS 号 ]:
952-23-8

[ 中文名 ]:
盐酸前黄素

[ 英文名 ]:
Proflavine hydrochloride

[中文别名 ]:

3,6-二氨基吖啶盐酸盐

[英文别名 ]:

chlorhydrate de diamino-3,6 acridine
3,6-Acridinediamine hydrochloride
N,N,N',N'-de-tetramethyl-acridine orange
acridine-3,6-diamine hydrochloride
3,6-diaminoacridine monohydrochloride
PROFLAVINHYDROCHLORIDE
3,6-Acridinediamine, hydrochloride (1:1)
Proflavine hydrochloride
3,6-Acridinediamine, hydrochloride (8CI)
3,6-diaminoacridine-hydrochloride

原黄素盐酸盐物理化学性质

[ 密度 ]:
1.346g/cm3

[ 沸点 ]:
506.9ºC at 760mmHg

[ 熔点 ]:
270 °C

[ 分子式 ]:
C₁₃H₁₂ClN₃

[ 分子量 ]:
245.708

[ 闪点 ]:
292.9ºC

[ 精确质量 ]:
245.071976

[ PSA ]:
64.93000

[ LogP ]:
4.51680

[ 储存条件 ]:
室温，干燥

原黄素盐酸盐MSDS

详细MSDS(安全技术说明书)

原黄素盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR9064000

CHEMICAL NAME :: Acridine, 3,6-diamino-, monohydrochloride

CAS REGISTRY NUMBER :: 952-23-8

LAST UPDATED :: 199603

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C13-H11-N3.Cl-H

MOLECULAR WEIGHT :: 245.73

WISWESSER LINE NOTATION :: T C666 BNJ EZ MZ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 190 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - hematuria

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5040 mg/kg/6W-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27 gm/kg/109W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 35 gm/kg/104W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 500 ug/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 204,323,1988 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

原黄素盐酸盐安全信息

[ 风险声明 (欧洲) ]:
R40

[ RTECS号 ]:
AR9064000

[ 海关编码 ]:
2933990090

原黄素盐酸盐合成路线

详细合成路线

原黄素盐酸盐上下游产品

原黄素盐酸盐上游产品

原黄素盐酸盐下游产品

原黄素盐酸盐海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%