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六氟异丙醇

六氟异丙醇用途

酯化作用试剂,肽和肽中间体的高强溶剂。使用GLC和电子捕获检测测定组织中的芳香酸.也可作为溶剂或清洗剂用于电子行业。其还凭借其可溶解各种聚合物（包括聚酯、聚酰胺、聚丙烯腈、聚缩醛树脂、和水解聚乙烯酯等）的能力而用于大量这些产品的分析中。

六氟异丙醇名称

[ CAS 号 ]:
920-66-1

[ 中文名 ]:
1,1,1,3,3,3-六氟-2-丙醇

[ 英文名 ]:
Hexafluoroisopropanol

[中文别名 ]:

[英文别名 ]:

2-Propanol, 1,1,1,2,3,3-hexafluoro-
1,1,1,2,3,3-Hexafluoropropan-2-ol
1,1,1,2,3,3-Hexafluoro-2-propanol
1,1,1,3,3,3-Hexafluoro-2-propanol
2-Propanol,1,1,1,3,3,3-hexafluoro-
EINECS 213-059-4
MFCD00011651
Hexafluoroisopropanol

六氟异丙醇物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
88.9±40.0 °C at 760 mmHg

[ 熔点 ]:
-4ºC

[ 分子式 ]:
C₃H₂F₆O

[ 分子量 ]:
168.038

[ 闪点 ]:
7.6±27.3 °C

[ 精确质量 ]:
168.000977

[ PSA ]:
20.23000

[ LogP ]:
2.06

[ 外观性状 ]:
无色液体

[ 蒸汽压 ]:
37.2±0.3 mmHg at 25°C

[ 折射率 ]:
1.269

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stable. Incompatible with strong acids, strong bases, alkali metals.

[ 水溶解性 ]:
1000 g/L (25 ºC)

六氟异丙醇MSDS

六氟异丙醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB6450000

CHEMICAL NAME :: 2-Propanol, 1,1,1,3,3,3-hexafluoro-

CAS REGISTRY NUMBER :: 920-66-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C3-H2-F6-O

MOLECULAR WEIGHT :: 168.05

WISWESSER LINE NOTATION :: FXFFYQXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1974 ppm/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Lungs, Thorax, or Respiration - dyspnea Blood - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571423

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1215,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1215,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03623 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83909 No. of Facilities: 14 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 367 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83909 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 135 (estimated) No. of Female Employees: 113 (estimated)

六氟异丙醇安全信息

[ 符号 ]:

GHS05, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H314-H361

[ 警示性声明 ]:
P260-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R20/22;R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 2922

[ WGK德国 ]:
2

[ RTECS号 ]:
UB6450000

[ 包装等级 ]:
II

[ 海关编码 ]:
29055910

六氟异丙醇合成路线

六氟异丙醇上下游产品

六氟异丙醇上游产品

六氟异丙醇下游产品

六氟异丙醇制备

参考生产厂家　美国杜邦公司。

六氟异丙醇海关

[ 海关编码 ]: 29055910

六氟异丙醇文献

Cardiolipin-incorporated liposomes with surface CRM197 for enhancing neuronal survival against neurotoxicity.

Int. J. Pharm. 473(1-2) , 334-44, (2014)

CRM197-grafted liposomes containing cardiolipin (CL) (CRM197/CL-liposomes) were used to enhance the permeability of neuron growth factor (NGF) across the blood-brain barrier (BBB) for promoting the ne...

The effects of organic solvents on the membrane-induced fibrillation of human islet amyloid polypeptide and on the inhibition of the fibrillation.

Biochim. Biophys. Acta 1838(12) , 3162-70, (2014)

The organic solvent dimethylsulphoxide (DMSO) and 1,1,1,3,3,3-hexafluoro-2-isopropanol (HFIP) have been widely used as a pre-treating agent of amyloid peptides and as a vehicle for water-insoluble inh...

Activated Schwann Cell-Like Cells on Aligned Fibrin-Poly(Lactic-Co-Glycolic Acid) Structures: A Novel Construct for Application in Peripheral Nerve Regeneration.

Cells Tissues Organs 200 , 287-99, (2015)

Tissue engineering approaches in nerve regeneration search for ways to support gold standard therapy (autologous nerve grafts) and to improve results by bridging nerve defects with different kinds of ...

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