阿朴色氨酸酶

阿朴色氨酸酶用途

色氨酸酶是一种细菌酶,催化色氨酸降解为吲哚、丙酮酸和氨[1]。

阿朴色氨酸酶名称

[ CAS 号 ]:
9024-00-4

[ 中文名 ]:
阿朴色氨酸酶

[ 英文名 ]:
Tryptophanase

[英文别名 ]:

MFCD00130539

阿朴色氨酸酶生物活性

[ 描述 ]:

色氨酸酶是一种细菌酶,催化色氨酸降解为吲哚、丙酮酸和氨[1]。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Rety S, et al. Structure of Escherichia coli tryptophanase purified from an alkaline-stressed bacterial culture. Acta Crystallogr F Struct Biol Commun. 2015 Nov;71(Pt 11):1378-83.

阿朴色氨酸酶物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 分子式 ]:
C₁₁H₁₂N₂O₆

[ 分子量 ]:
268.223

[ 精确质量 ]:
268.069550

[ LogP ]:
0.02

[ 折射率 ]:
1.680

阿朴色氨酸酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

阿朴色氨酸酶文献

Inhibition of Escherichia coli tryptophan indole-lyase by tryptophan homologues.

Arch. Biochem. Biophys. 560 , 20-6, (2014)

We have designed, synthesized and evaluated homotryptophan analogues as possible mechanism-based inhibitors for Escherichia coli tryptophan indole-lyase (tryptophanase, TIL, E.C. 4.1.99.1). As a quino...

Reaction pathway of tryptophanase-catalyzed L-tryptophan synthesis from D-serine.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(29) , 3289-95, (2011)

Tryptophanase, L-tryptophan indole-lyase with extremely absolute stereospecificity, can change the stereospecificity in concentrated diammonium hydrogenphosphate solution. While tryptophanase is not i...

Indole production by the tryptophanase TnaA in Escherichia coli is determined by the amount of exogenous tryptophan.

Microbiology 159(Pt 2) , 402-10, (2013)

The signalling molecule indole occurs in significant amounts in the mammalian intestinal tract and regulates diverse microbial processes, including bacterial motility, biofilm formation, antibiotic re...

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