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4a,5-二氢洛伐他汀

4a,5-二氢洛伐他汀名称

[ CAS 号 ]:
77517-29-4

[ 中文名 ]:
洛伐他汀相关物质A

[ 英文名 ]:
dihydromevinolin

4a,5-二氢洛伐他汀物理化学性质

[ 密度 ]:
1.1g/cm3

[ 沸点 ]:
534.8ºC at 760 mmHg

[ 分子式 ]:
C₂₄H₃₈O₅

[ 分子量 ]:
406.55600

[ 闪点 ]:
174.5ºC

[ 精确质量 ]:
406.27200

[ PSA ]:
72.83000

[ LogP ]:
4.27540

[ 折射率 ]:
1.52

4a,5-二氢洛伐他汀安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

4a,5-二氢洛伐他汀合成路线

详细合成路线

4a,5-二氢洛伐他汀上下游产品

4a,5-二氢洛伐他汀上游产品

4a,5-二氢洛伐他汀下游产品

4a,5-二氢洛伐他汀文献

Total synthesis and biological evaluation of structural analogues of compactin and dihydromevinolin.

J. Med. Chem. 30(10) , 1858-73, (1987)

The full experimental details for the total synthesis of (+)-compactin and 19 structural analogues are reported. We have evaluated three classes of analogues as inhibitors of 3-hydroxy-3-methylglutary...

Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus.

J. Antibiot. 34(5) , 507-12, (1981)

A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a,5-dihydromevinolin containing a trans-fused octahyd...

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