4a,5-二氢洛伐他汀

更新时间:2024-01-05 19:17:33

4a,5-二氢洛伐他汀结构式
4a,5-二氢洛伐他汀结构式
品牌特惠专场
常用名 4a,5-二氢洛伐他汀 英文名 dihydromevinolin
CAS号 77517-29-4 分子量 406.55600
密度 1.1g/cm3 沸点 534.8ºC at 760 mmHg
分子式 C24H38O5 熔点 N/A
MSDS N/A 闪点 174.5ºC

 4a,5-二氢洛伐他汀名称

中文名 洛伐他汀相关物质A
英文名 (1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate

 4a,5-二氢洛伐他汀物理化学性质

密度 1.1g/cm3
沸点 534.8ºC at 760 mmHg
分子式 C24H38O5
分子量 406.55600
闪点 174.5ºC
精确质量 406.27200
PSA 72.83000
LogP 4.27540
折射率 1.52

 4a,5-二氢洛伐他汀安全信息

危险品运输编码 NONH for all modes of transport

 4a,5-二氢洛伐他汀合成线路

 4a,5-二氢洛伐他汀上下游产品

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 4a,5-二氢洛伐他汀文献2

更多文献
Total synthesis and biological evaluation of structural analogues of compactin and dihydromevinolin.

J. Med. Chem. 30(10) , 1858-73, (1987)

The full experimental details for the total synthesis of (+)-compactin and 19 structural analogues are reported. We have evaluated three classes of analogues as inhibitors of 3-hydroxy-3-methylglutary...

Dihydromevinolin, a potent hypocholesterolemic metabolite produced by Aspergillus terreus.

J. Antibiot. 34(5) , 507-12, (1981)

A new, potent hypocholesterolemic agent is produced by cultures of Aspergillus terreus. The isolation of the compound and its characterization as 4a,5-dihydromevinolin containing a trans-fused octahyd...