乙酰胺苯砜
乙酰胺苯砜名称
[ CAS 号 ]:
77-46-3
[ 中文名 ]:
乙酰胺苯砜
[ 英文名 ]:
acedapsone
[英文别名 ]:
- Acetamin
- Acedapsone
- Hansolar
- 4,4'-diacetamidodiphenyl sulphone
- 4,4'-bis(acetylamino)diphenyl sulfone
- N,N'-[4,4'-sulfinylbis(4,1-phenylene)]diacetamide
- DADDS
- Diacetyldapsone
- Sulfadiamine
- 4,4'''-sulfonylbis(acetanilide)
乙酰胺苯砜物理化学性质
[ 密度 ]:
1.362g/cm3
[ 沸点 ]:
661ºC at 760 mmHg
[ 熔点 ]:
289-292°
[ 分子式 ]:
C16H16N2O4S
[ 分子量 ]:
332.37400
[ 闪点 ]:
353.6ºC
[ 精确质量 ]:
332.08300
[ PSA ]:
100.72000
[ LogP ]:
3.66300
[ 折射率 ]:
1.625
乙酰胺苯砜毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AE7175000
- CHEMICAL NAME :
- Acetanilide, 4',4'''-sulfonylbis-
- CAS REGISTRY NUMBER :
- 77-46-3
- BEILSTEIN REFERENCE NO. :
- 2164071
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H16-N2-O4-S
- MOLECULAR WEIGHT :
- 332.40
- WISWESSER LINE NOTATION :
- 1VMR DSWR DMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 61,617,1939 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4200 mg/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - tumors Blood - lymphoma, including Hodgkin's disease
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 24,149,1960
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