氯化失车菊素-3-O-葡萄糖苷

氯化失车菊素-3-O-葡萄糖苷用途

矢车菊素-3-O-葡萄糖苷 (Kuromanin chloride) 来源于桑叶,具有提高血糖浓度、维持脂质代谢平衡以降低肥胖的作用。

氯化失车菊素-3-O-葡萄糖苷作用

现代药理学研究证明矢车菊素-3-O-葡萄糖苷具有显著的抗氧化、抗肿瘤、保护神经系统、恢复短暂性视力减弱等多种医疗保健作用。另有研究发现矢车菊素-3-O-葡萄糖苷可作为植物保护剂，保护棉花叶片免受棉铃虫的危害。
黑豆皮中矢车菊素-3-O-葡萄糖苷能够减少3T3-L1脂肪细胞胞内的活性氧物质的产生，从而剂量依赖地改善H2O2或者TNF-α诱导的胰岛素耐受性；同时能够减少视黄醇结合蛋白在Ⅱ型糖尿病大鼠的表达，改善高血糖症和提高胰岛素敏感度，从而改善糖尿病症状。

氯化失车菊素-3-O-葡萄糖苷名称

[ CAS 号 ]:
7084-24-4

[ 中文名 ]:
矢车菊素-3-O-葡萄糖苷

[ 英文名 ]:
Cyanidin-3-O-glucoside chloride

[中文别名 ]:

[英文别名 ]:

Cyanidin Chloride 3-Glucoside
cyanidin 3-O-beta-D-glucoside
Kuromanin
Kuromanin chloride
Cyanidin 3-O-glucoside chloride
Kuromanin (chloride)

氯化失车菊素-3-O-葡萄糖苷生物活性

[ 描述 ]:

矢车菊素-3-O-葡萄糖苷 (Kuromanin chloride) 来源于桑叶,具有提高血糖浓度、维持脂质代谢平衡以降低肥胖的作用。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

天然产物 >> 黄酮类化合物

研究领域 >> 代谢疾病

[参考文献]

[1]. Ha -Na Na, et al. Reduction of adenovirus 36-induced obesity andin?ammation by mulberry extract. Microbiol Immunol 2014; 58: 303–306

[相关活性小分子]

氯化失车菊素-3-O-葡萄糖苷物理化学性质

[ 分子式 ]:
C₂₁H₂₁ClO₁₁

[ 分子量 ]:
484.838

[ 精确质量 ]:
484.077240

[ PSA ]:
193.44000

[ 外观性状 ]:
棕色晶体粉末

[ 储存条件 ]:
−20°C

氯化失车菊素-3-O-葡萄糖苷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DK1270000

CHEMICAL NAME :: 1-Benzopyrylium, 5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3-(beta-D-gluco pyranosyloxy)-, chloride

CAS REGISTRY NUMBER :: 7084-24-4

LAST UPDATED :: 199603

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H21-O11.Cl

MOLECULAR WEIGHT :: 484.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4229439

氯化失车菊素-3-O-葡萄糖苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
DK1270000

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氯化失车菊素-3-O-葡萄糖苷文献

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