3-甲氨基丙胺
3-甲氨基丙胺名称
[ CAS 号 ]:
6291-84-5
[ 中文名 ]:
3-甲氨基丙胺
[ 英文名 ]:
N-METHYL-1,3-PROPANEDIAMINE
[中文别名 ]:
[英文别名 ]:
- N-METHYL-1,3-PROPANEDIAMINE
- MFCD00008209
- 1,3-Propanediamine, N-methyl-
- N-methylpropane-1,3-diamine
- N-Methyl-propane-1,3-diamine
- N'-methylpropane-1,3-diamine
- EINECS 228-544-6
3-甲氨基丙胺物理化学性质
[ 密度 ]:
0.8±0.1 g/cm3
[ 沸点 ]:
140.0±0.0 °C at 760 mmHg
[ 熔点 ]:
-72 °C
[ 分子式 ]:
C4H12N2
[ 分子量 ]:
88.151
[ 闪点 ]:
35.6±0.0 °C
[ 精确质量 ]:
88.100044
[ PSA ]:
38.05000
[ LogP ]:
-0.79
[ 外观性状 ]:
无色液体带有氨气味
[ 蒸汽压 ]:
6.3±0.2 mmHg at 25°C
[ 折射率 ]:
1.431
[ 储存条件 ]:
Flammables area
[ 水溶解性 ]:
水溶性:完全混溶;混溶:醇;可溶于:乙醚
3-甲氨基丙胺MSDS
3-甲氨基丙胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX8242500
- CHEMICAL NAME :
- 1,3-Propanediamine, N-methyl-
- CAS REGISTRY NUMBER :
- 6291-84-5
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C4-H12-N2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 951 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - hematuria
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555335
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >189 mg/m3/6H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555335
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 282 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - hematuria
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555335 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1300 mg/kg/13D-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555335
3-甲氨基丙胺安全信息
[ 符号 ]:
GHS02, GHS05, GHS06
[ 信号词 ]:
Danger
[ 危害声明 ]:
H226-H302-H312-H314-H330
[ 警示性声明 ]:
P260-P280-P284-P305 + P351 + P338-P310
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
T+:Verytoxic;
[ 风险声明 (欧洲) ]:
R10;R22;R26;R34
[ 安全声明 (欧洲) ]:
S16-S26-S36/37-S45
[ 危险品运输编码 ]:
UN 2734 8/PG 2
[ WGK德国 ]:
3
[ RTECS号 ]:
TX8242500
[ 包装等级 ]:
II
[ 危险类别 ]:
8
3-甲氨基丙胺合成路线
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3-甲氨基丙胺上游产品
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3-甲氨基丙胺文献
PLoS ONE 10 , e0129273, (2015)
The SLC45A2 gene encodes a Membrane-Associated Transporter Protein (MATP). Mutations of this gene cause oculocutaneous albinism type 4 (OCA4). However, the molecular mechanism of its action in melanog...
Lipases as catalysts in synthesis of fine chemicals.Methods Mol. Biol. 861 , 445-56, (2012)
The application of lipases as catalysts in the synthesis of an intermediate of alfuzosin and lapyrium chloride is described. In the first case, the one-pot procedure to obtain the intermediate involve...
Synthesis and characterization of two aluminophosphates templated byN-methyl-1, 3-diaminopropane. Tuel A, et al.J. Solid State Chem. 178(3) , 782-791, (2005)
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