Penicillin G Procaine
Penicillin G Procaine用途
Penicillin G Procaine名称
[ CAS 号 ]:
6130-64-9
[ 中文名 ]:
普鲁卡因青霉素 G
[ 英文名 ]:
Penicillin G Procaine
[中文别名 ]:
[英文别名 ]:
- Procaine penicilline G hydrate
- MFCD00150771
Penicillin G Procaine生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
Penicillin G Procaine物理化学性质
[ 密度 ]:
1.255-1.256 g/cm3 (20ºC)
[ 沸点 ]:
663.3ºC at 760 mmHg
[ 熔点 ]:
106-110ºC
[ 分子式 ]:
C29H40N4O7S
[ 分子量 ]:
589.72300
[ 闪点 ]:
355ºC
[ 精确质量 ]:
589.27000
[ PSA ]:
187.80000
[ LogP ]:
3.37270
[ 外观性状 ]:
粉末
[ 储存条件 ]:
-20℃
Penicillin G Procaine毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XH9450000
- CAS REGISTRY NUMBER :
- 6130-64-9
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C16-H18-N2-O4-S.C13-H20-N2-O2.H2-O
- MOLECULAR WEIGHT :
- 588.79
- WISWESSER LINE NOTATION :
- T45 ANV E5TJ CMV1R& F F GVQ &ZR DVO2N2&2&QH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - interstitial nephritis Skin and Appendages - dermatitis, allergic (after systemic exposure)
- REFERENCE :
- JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 147,1139,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 5,152,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 97 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 5,152,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 146 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,306,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 1,28,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 119 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,31,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,31,1959
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >545 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 3,421,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 5,152,1955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7431 No. of Facilities: 402 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 4914 (estimated) No. of Female Employees: 110 (estimated)
Penicillin G Procaine安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H317
[ 警示性声明 ]:
P280
[ 危害码 (欧洲) ]:
Xn
[ 风险声明 (欧洲) ]:
R42/43
[ 安全声明 (欧洲) ]:
36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ RTECS号 ]:
XH9450000
相关药品:
推荐生产厂家/供应商:
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥2677.9/100mg
¥882.9/25mg
¥308.9/1ml
¥4737.9/250mg
联系人:阿拉丁李高志
产品详情:青霉素G普鲁卡因水合物
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥392.0/5mg
联系人:夏言
产品详情:[Perfemiker]Penicillin G Procaine,BR
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相关化合物
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