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对甲氧基苯乙胺

对甲氧基苯乙胺用途

【用途一】
利托君的中间体。

对甲氧基苯乙胺名称

[ CAS 号 ]:
55-81-2

[ 中文名 ]:
2-(4-甲氧苯基)乙胺

[ 英文名 ]:
4-Methoxyphenylethylamine

[中文别名 ]:

[英文别名 ]:

4-Methoxyphenethylamine
MFCD00008192
EINECS 200-245-5
4-Methoxyphenylethylamine
2-(4-Methoxyphenyl)ethanamine
4-Methoxy-β-phenylethylamine
Benzeneethanamine, 4-methoxy-

对甲氧基苯乙胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
255.2±0.0 °C at 760 mmHg

[ 熔点 ]:
249-251°C

[ 分子式 ]:
C₉H₁₃NO

[ 分子量 ]:
151.206

[ 闪点 ]:
105.3±13.6 °C

[ 精确质量 ]:
151.099716

[ PSA ]:
35.25000

[ LogP ]:
1.37

[ 外观性状 ]:
liquid | light yellow

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.526

[ 储存条件 ]:
2-8°C

对甲氧基苯乙胺MSDS

对甲氧基苯乙胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH7875000

CHEMICAL NAME :: Phenethylamine, p-methoxy-

CAS REGISTRY NUMBER :: 55-81-2

BEILSTEIN REFERENCE NO. :: 0508967

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H13-N-O

MOLECULAR WEIGHT :: 151.23

WISWESSER LINE NOTATION :: Z2R DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7150 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1358 (estimated) No. of Female Employees: 956 (estimated)

对甲氧基苯乙胺安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 2735 8/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
SH7875000

[ 海关编码 ]:
29222900

对甲氧基苯乙胺合成路线

对甲氧基苯乙胺上下游产品

对甲氧基苯乙胺上游产品

对甲氧基苯乙胺下游产品

对甲氧基苯乙胺海关

[ 海关编码 ]: 2922299090

[ 中文概述 ]:
2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

对甲氧基苯乙胺文献

Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis.

Biochemistry 40 , 14215, (2001)

Cytochrome P450 (P450) 2D6 oxidizes a wide variety of drugs typically at a distance of 5-7 A from a basic nitrogen on the substrate. To investigate the determinants of P450 2D6 catalysis, we analyzed ...

Electrochemical Investigation of oligonucleotide-DNA hybridization on poly(4-methoxyphenethylamine).

Int. J. Mol. Sci. 9(7) , 1173-88, (2008)

This work describes the immobilization of purine and pyrimidine bases and immobilization/hybridization of synthetic oligonucleotides on graphite electrodes modified with poly(4-methoxyphenethylamine) ...

Selectivity of 4-methoxyphenethylamine derivatives as inhibitors of monoamine oxidase.

J. Pharm. Sci. 65(10) , 1539-40, (1976)

It has been established that the oxidative deamination of tyramine by monoamine xodase is inhibited by (+/-)-4-methoxy-beta-hydroxyphenethylamine and its N-methylated derivatives. This particular seri...

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